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SMILES: Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(C(=O)N4CCC(CC4)S(C)(=O)=O)c3Cl)cc12)C(F)(F)F

InChI Key: InChIKey=PMEHDBLITJSZNF-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292718   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM292718
PNG
(US10106501, Example A1-11)
Show SMILES Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(C(=O)N4CCC(CC4)S(C)(=O)=O)c3Cl)cc12)C(F)(F)F
Show InChI InChI=1S/C25H25Cl2F3N2O3S/c1-14-10-15(25(28,29)30)11-22-19(14)12-16(31(22)2)13-20-21(26)5-4-18(23(20)27)24(33)32-8-6-17(7-9-32)36(3,34)35/h4-5,10-12,17H,6-9,13H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...

US Patent US10106501 (2018)


BindingDB Entry DOI: 10.7270/Q2G44SBV
More data for this
Ligand-Target Pair