null

SMILES: COc1ccc(CSc2nnc(SCc3ccc(OC)cc3)s2)cc1

InChI Key: InChIKey=UDLMBXIYIDCCSA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM29310 (dithioether 1,3,4-thiadiazole, 8c) Show SMILES COc1ccc(CSc2nnc(SCc3ccc(OC)cc3)s2)cc1 Show InChI InChI=1S/C18H18N2O2S3/c1-21-15-7-3-13(4-8-15)11-23-17-19-20-18(25-17)24-12-14-5-9-16(22-2)10-6-14/h3-10H,11-12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research					Assay Description Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...				J Med Chem 52: 1943-52 (2009) Article DOI: 10.1021/jm801503n BindingDB Entry DOI: 10.7270/Q20Z71MD
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM29310 (dithioether 1,3,4-thiadiazole, 8c) Show SMILES COc1ccc(CSc2nnc(SCc3ccc(OC)cc3)s2)cc1 Show InChI InChI=1S/C18H18N2O2S3/c1-21-15-7-3-13(4-8-15)11-23-17-19-20-18(25-17)24-12-14-5-9-16(22-2)10-6-14/h3-10H,11-12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research					Assay Description Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...				J Med Chem 52: 1943-52 (2009) Article DOI: 10.1021/jm801503n BindingDB Entry DOI: 10.7270/Q20Z71MD
					More data for this Ligand-Target Pair