BDBM293227 US10106501, Example CT-6

SMILES: COC1CCN(CC1)C(=O)c1ccc(Cl)c(Cc2nc3c(C)cc(cn3c2C)C(F)(F)F)c1Cl

InChI Key: InChIKey=GISVNJPOTVYTJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM293227 (US10106501, Example CT-6) Show SMILES COC1CCN(CC1)C(=O)c1ccc(Cl)c(Cc2nc3c(C)cc(cn3c2C)C(F)(F)F)c1Cl Show InChI InChI=1S/C24H24Cl2F3N3O2/c1-13-10-15(24(27,28)29)12-32-14(2)20(30-22(13)32)11-18-19(25)5-4-17(21(18)26)23(33)31-8-6-16(34-3)7-9-31/h4-5,10,12,16H,6-9,11H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...				US Patent US10106501 (2018) BindingDB Entry DOI: 10.7270/Q2G44SBV
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