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BDBM293268 US10106504, Example 5

SMILES: Cc1ccc(cc1)-c1c([C@H](OC(C)(C)C)C(O)=O)c(C)nc(C)c1-c1ccc(OCc2ccc(F)cc2)cc1

InChI Key: InChIKey=UJMUTMLFYRVRNM-HKBQPEDESA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293268   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HIV-1 Protease Chain A


(Human immunodeficiency virus type 1)		BDBM293268
PNG
(US10106504, Example 5)
Show SMILES Cc1ccc(cc1)-c1c([C@H](OC(C)(C)C)C(O)=O)c(C)nc(C)c1-c1ccc(OCc2ccc(F)cc2)cc1 |r|
Show InChI InChI=1S/C33H34FNO4/c1-20-7-11-25(12-8-20)30-28(21(2)35-22(3)29(30)31(32(36)37)39-33(4,5)6)24-13-17-27(18-14-24)38-19-23-9-15-26(34)16-10-23/h7-18,31H,19H2,1-6H3,(H,36,37)/t31-/m0/s1
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 550n/an/a7.55n/a



ViiV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10106504 (2018)


BindingDB Entry DOI: 10.7270/Q2BC41K2
More data for this
Ligand-Target Pair