BDBM293275 US10106504, Example 12
SMILES: COCCNCc1nc(C)c([C@H](OC(C)(C)C)C(O)=O)c(-c2ccc3OCCCc3c2)c1-c1ccc(OCCc2ccc(F)cc2)cc1
InChI Key: InChIKey=VLSPYMFCXQSEML-QNGWXLTQSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HIV-1 Protease Chain A (Human immunodeficiency virus type 1) | BDBM293275 (US10106504, Example 12) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 7 | n/a | n/a | 7.55 | n/a |
ViiV HEALTHCARE UK (NO.5) LIMITED US Patent | Assay Description A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi... | US Patent US10106504 (2018) BindingDB Entry DOI: 10.7270/Q2BC41K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 Protease Chain A (Human immunodeficiency virus type 1) | BDBM293275 (US10106504, Example 12) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <100 | n/a | n/a | 7.55 | n/a |
ViiV HEALTHCARE UK (NO.5) LIMITED US Patent | Assay Description A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi... | US Patent US10106504 (2018) BindingDB Entry DOI: 10.7270/Q2BC41K2 | |||||||||||
More data for this Ligand-Target Pair |