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SMILES: Clc1ccc(CCC(=O)N2CCC[C@H]2C(=O)NCc2cccs2)cc1

InChI Key: InChIKey=MXZLFWSZVDVKTJ-KRWDZBQOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29355   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM29355
PNG
(proline scaffold, 4)
Show SMILES Clc1ccc(CCC(=O)N2CCC[C@H]2C(=O)NCc2cccs2)cc1 |r|
Show InChI InChI=1S/C19H21ClN2O2S/c20-15-8-5-14(6-9-15)7-10-18(23)22-11-1-4-17(22)19(24)21-13-16-3-2-12-25-16/h2-3,5-6,8-9,12,17H,1,4,7,10-11,13H2,(H,21,24)/t17-/m0/s1
PDB

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antibodypedia
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UniChem

Similars
Article
PubMed
n/an/a>4.00E+5 7.00E+5n/an/an/a7.437



University of Kalmar



Assay Description
SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...

J Med Chem 52: 2708-15 (2009)


Article DOI: 10.1021/jm8011849
BindingDB Entry DOI: 10.7270/Q2H130B7
More data for this
Ligand-Target Pair