null

SMILES: OC(=O)c1ccncc1NCC1CCOc2cc(ccc12)N1CCCc2ccccc12

InChI Key: InChIKey=NOOJTVYXMUCAIS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM293674 (3-({[7-(1,2,3,4-tetrahydroquinolin-1-yl)-3,4-dihyd...) Show SMILES OC(=O)c1ccncc1NCC1CCOc2cc(ccc12)N1CCCc2ccccc12 Show InChI InChI=1S/C25H25N3O3/c29-25(30)21-9-11-26-16-22(21)27-15-18-10-13-31-24-14-19(7-8-20(18)24)28-12-3-5-17-4-1-2-6-23(17)28/h1-2,4,6-9,11,14,16,18,27H,3,5,10,12-13,15H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293674 (3-({[7-(1,2,3,4-tetrahydroquinolin-1-yl)-3,4-dihyd...) Show SMILES OC(=O)c1ccncc1NCC1CCOc2cc(ccc12)N1CCCc2ccccc12 Show InChI InChI=1S/C25H25N3O3/c29-25(30)21-9-11-26-16-22(21)27-15-18-10-13-31-24-14-19(7-8-20(18)24)28-12-3-5-17-4-1-2-6-23(17)28/h1-2,4,6-9,11,14,16,18,27H,3,5,10,12-13,15H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair