BindingDB logo
myBDB logout

null

SMILES: Cc1c(F)cccc1-c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=RLXQNDVSCMTPQA-INIZCTEOSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293700   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))		BDBM293700
PNG
(3-({[(4R)-7-(3-fluoro-2-methylphenyl)-3,4-dihydro-...)
Show SMILES Cc1c(F)cccc1-c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r|
Show InChI InChI=1S/C23H21FN2O3/c1-14-17(3-2-4-20(14)24)15-5-6-18-16(8-10-29-22(18)11-15)12-26-21-13-25-9-7-19(21)23(27)28/h2-7,9,11,13,16,26H,8,10,12H2,1H3,(H,27,28)/t16-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10106534 (2018)


BindingDB Entry DOI: 10.7270/Q2JW8GZX
More data for this
Ligand-Target Pair