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SMILES: O=C(Cc1ccc2OCOc2c1)N1CCC[C@H]1C(=O)NCc1cccs1

InChI Key: InChIKey=IQGHPVWVMXPGEW-HNNXBMFYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29371   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM29371
PNG
(proline scaffold, 20)
Show SMILES O=C(Cc1ccc2OCOc2c1)N1CCC[C@H]1C(=O)NCc1cccs1 |r|
Show InChI InChI=1S/C19H20N2O4S/c22-18(10-13-5-6-16-17(9-13)25-12-24-16)21-7-1-4-15(21)19(23)20-11-14-3-2-8-26-14/h2-3,5-6,8-9,15H,1,4,7,10-12H2,(H,20,23)/t15-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>4.00E+5 2.50E+5n/an/an/a7.437



University of Kalmar



Assay Description
SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...

J Med Chem 52: 2708-15 (2009)


Article DOI: 10.1021/jm8011849
BindingDB Entry DOI: 10.7270/Q2H130B7
More data for this
Ligand-Target Pair