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SMILES: Cc1ccc(Oc2ccc3[C@H](CNc4cnccc4C(O)=O)CCCc3c2)c(F)c1

InChI Key: InChIKey=QOTHRXKHLOLBSR-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM293724 (3-({[(1R)-6-(2-fluoro-4-methylphenoxy)-1,2,3,4- | ...) Show SMILES Cc1ccc(Oc2ccc3[C@H](CNc4cnccc4C(O)=O)CCCc3c2)c(F)c1 |r| Show InChI InChI=1S/C24H23FN2O3/c1-15-5-8-23(21(25)11-15)30-18-6-7-19-16(12-18)3-2-4-17(19)13-27-22-14-26-10-9-20(22)24(28)29/h5-12,14,17,27H,2-4,13H2,1H3,(H,28,29)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293724 (3-({[(1R)-6-(2-fluoro-4-methylphenoxy)-1,2,3,4- | ...) Show SMILES Cc1ccc(Oc2ccc3[C@H](CNc4cnccc4C(O)=O)CCCc3c2)c(F)c1 |r| Show InChI InChI=1S/C24H23FN2O3/c1-15-5-8-23(21(25)11-15)30-18-6-7-19-16(12-18)3-2-4-17(19)13-27-22-14-26-10-9-20(22)24(28)29/h5-12,14,17,27H,2-4,13H2,1H3,(H,28,29)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair