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SMILES: CN(c1ccc(cc1)C#C)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=LRXZHFZYUNXDDK-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM293784 (3-({[(4R)-7-[(4-ethynylphenyl)(methyl)amino]-3,4-d...) Show SMILES CN(c1ccc(cc1)C#C)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C25H23N3O3/c1-3-17-4-6-19(7-5-17)28(2)20-8-9-21-18(11-13-31-24(21)14-20)15-27-23-16-26-12-10-22(23)25(29)30/h1,4-10,12,14,16,18,27H,11,13,15H2,2H3,(H,29,30)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293784 (3-({[(4R)-7-[(4-ethynylphenyl)(methyl)amino]-3,4-d...) Show SMILES CN(c1ccc(cc1)C#C)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C25H23N3O3/c1-3-17-4-6-19(7-5-17)28(2)20-8-9-21-18(11-13-31-24(21)14-20)15-27-23-16-26-12-10-22(23)25(29)30/h1,4-10,12,14,16,18,27H,11,13,15H2,2H3,(H,29,30)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair