null
SMILES: CN(c1c(C)noc1C)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1
InChI Key: InChIKey=OJZIYBMAYLHTHU-KRWDZBQOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 6B (Homo sapiens (Human)) | BDBM293824 (3-({[(1R)-6-[(dimethyl-1,2-oxazol-4-yl)(methyl)ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Celgene Quanticel Research, Inc. US Patent | Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com... | US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM293824 (3-({[(1R)-6-[(dimethyl-1,2-oxazol-4-yl)(methyl)ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | 25 |
Celgene Quanticel Research, Inc. US Patent | Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ... | US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX | |||||||||||
More data for this Ligand-Target Pair |