BDBM293836 3-({[(4R)-7-[(4-methoxyphenyl)(methyl)amino]-3,4-dihydro-2H-1-::US10106534, Example 178

SMILES: COc1ccc(cc1)N(C)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=LUSJYIUAVSJRDT-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293836 (3-({[(4R)-7-[(4-methoxyphenyl)(methyl)amino]-3,4-d...) Show SMILES COc1ccc(cc1)N(C)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C24H25N3O4/c1-27(17-3-6-19(30-2)7-4-17)18-5-8-20-16(10-12-31-23(20)13-18)14-26-22-15-25-11-9-21(22)24(28)29/h3-9,11,13,15-16,26H,10,12,14H2,1-2H3,(H,28,29)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair