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SMILES: CN1CCN(CC1)c1nc2nc([N+]#[C-])c(Cl)cc2n2cnnc12

InChI Key: InChIKey=GXQUMWUCJOISBD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294371   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))		BDBM294371
PNG
(US9586959, Compound 21)
Show SMILES CN1CCN(CC1)c1nc2nc([N+]#[C-])c(Cl)cc2n2cnnc12
Show InChI InChI=1S/C14H13ClN8/c1-16-11-9(15)7-10-12(18-11)19-13(14-20-17-8-23(10)14)22-5-3-21(2)4-6-22/h7-8H,3-6H2,2H3
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US Patent
n/an/a 270n/an/an/an/a7.525



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US Patent


Assay Description
In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...

US Patent US9586959 (2017)


BindingDB Entry DOI: 10.7270/Q2C53NWD
More data for this
Ligand-Target Pair