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SMILES: CN1CCN(CC1)c1nc2ncc(Cl)cc2c2nc(nn12)C1CC1

InChI Key: InChIKey=RETNOQVKSOUDLS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294444   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM294444
PNG
(US9586959, Compound 38)
Show SMILES CN1CCN(CC1)c1nc2ncc(Cl)cc2c2nc(nn12)C1CC1
Show InChI InChI=1S/C16H18ClN7/c1-22-4-6-23(7-5-22)16-20-14-12(8-11(17)9-18-14)15-19-13(10-2-3-10)21-24(15)16/h8-10H,2-7H2,1H3
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US Patent
n/an/a>1.00E+8n/an/an/an/a7.427



C&C RESEARCH LABORATORIES

US Patent


Assay Description
Each compound of the present invention prepared in the examples was prepared in DMSO into concentrations of 0.02, 0.06, 0.3 and 2 mM. 10 uL of the pr...

US Patent US9586959 (2017)


BindingDB Entry DOI: 10.7270/Q2C53NWD
More data for this
Ligand-Target Pair