BDBM294794 US10112899, Example 265

SMILES: Cc1ccc(cc1)-c1c(C)c2CN(Cc2c(C)c1[C@H](OC(C)(C)C)C(O)=O)C(=O)c1ccc2OCOc2c1

InChI Key: InChIKey=MZKJYHGRLJPDOS-NDEPHWFRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM294794 (US10112899, Example 265) Show SMILES Cc1ccc(cc1)-c1c(C)c2CN(Cc2c(C)c1[C@H](OC(C)(C)C)C(O)=O)C(=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C31H33NO6/c1-17-7-9-20(10-8-17)26-18(2)22-14-32(29(33)21-11-12-24-25(13-21)37-16-36-24)15-23(22)19(3)27(26)28(30(34)35)38-31(4,5)6/h7-13,28H,14-16H2,1-6H3,(H,34,35)/t28-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ViiV HEALTHCARE UK LIMITED US Patent					Assay Description Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...				US Patent US10112899 (2018) BindingDB Entry DOI: 10.7270/Q2KP8465
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