null

SMILES: Cc1ccccc1N1CCN(CCn2c3ccccc3n(-c3ccccc3C)c2=O)CC1

InChI Key: InChIKey=YKWLQTJNNWZMOA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29538 (benzimidazolone scaffold, 8f) Show SMILES Cc1ccccc1N1CCN(CCn2c3ccccc3n(-c3ccccc3C)c2=O)CC1 |(1.69,4.1,;1.69,5.64,;3.03,6.41,;3.03,7.95,;1.69,8.72,;.36,7.95,;.36,6.41,;-.97,5.64,;-2.31,6.41,;-3.64,5.64,;-3.64,4.1,;-4.97,3.33,;-6.31,4.1,;-7.64,3.33,;-8.89,4.29,;-9.05,5.82,;-10.46,6.45,;-11.7,5.54,;-11.54,4.01,;-10.13,3.38,;-9.66,1.86,;-10.57,.62,;-12.09,.87,;-13.07,-.32,;-12.53,-1.76,;-11.01,-2.01,;-10.03,-.82,;-8.51,-1.07,;-8.12,1.86,;-7.21,.61,;-2.31,3.32,;-.97,4.1,)| Show InChI InChI=1S/C27H30N4O/c1-21-9-3-5-11-23(21)29-18-15-28(16-19-29)17-20-30-25-13-7-8-14-26(25)31(27(30)32)24-12-6-4-10-22(24)2/h3-14H,15-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	375	-9.11	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29538 (benzimidazolone scaffold, 8f) Show SMILES Cc1ccccc1N1CCN(CCn2c3ccccc3n(-c3ccccc3C)c2=O)CC1 |(1.69,4.1,;1.69,5.64,;3.03,6.41,;3.03,7.95,;1.69,8.72,;.36,7.95,;.36,6.41,;-.97,5.64,;-2.31,6.41,;-3.64,5.64,;-3.64,4.1,;-4.97,3.33,;-6.31,4.1,;-7.64,3.33,;-8.89,4.29,;-9.05,5.82,;-10.46,6.45,;-11.7,5.54,;-11.54,4.01,;-10.13,3.38,;-9.66,1.86,;-10.57,.62,;-12.09,.87,;-13.07,-.32,;-12.53,-1.76,;-11.01,-2.01,;-10.03,-.82,;-8.51,-1.07,;-8.12,1.86,;-7.21,.61,;-2.31,3.32,;-.97,4.1,)| Show InChI InChI=1S/C27H30N4O/c1-21-9-3-5-11-23(21)29-18-15-28(16-19-29)17-20-30-25-13-7-8-14-26(25)31(27(30)32)24-12-6-4-10-22(24)2/h3-14H,15-20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair