BDBM29546 benzimidazolone scaffold, 15d

SMILES: COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1

InChI Key: InChIKey=YERGVXFJQYPXLJ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29546 (benzimidazolone scaffold, 15d) Show SMILES COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C21H26N4O2/c1-27-20-10-5-4-9-19(20)24-15-13-23(14-16-24)11-6-12-25-18-8-3-2-7-17(18)22-21(25)26/h2-5,7-10H,6,11-16H2,1H3,(H,22,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5HT7 receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometry				Eur J Med Chem 85: 716-26 (2014) Article DOI: 10.1016/j.ejmech.2014.08.023 BindingDB Entry DOI: 10.7270/Q2DZ09Z8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29546 (benzimidazolone scaffold, 15d) Show SMILES COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C21H26N4O2/c1-27-20-10-5-4-9-19(20)24-15-13-23(14-16-24)11-6-12-25-18-8-3-2-7-17(18)22-21(25)26/h2-5,7-10H,6,11-16H2,1H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	-12.0	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM29546 (benzimidazolone scaffold, 15d) Show SMILES COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C21H26N4O2/c1-27-20-10-5-4-9-19(20)24-15-13-23(14-16-24)11-6-12-25-18-8-3-2-7-17(18)22-21(25)26/h2-5,7-10H,6,11-16H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometry				Eur J Med Chem 85: 716-26 (2014) Article DOI: 10.1016/j.ejmech.2014.08.023 BindingDB Entry DOI: 10.7270/Q2DZ09Z8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29546 (benzimidazolone scaffold, 15d) Show SMILES COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C21H26N4O2/c1-27-20-10-5-4-9-19(20)24-15-13-23(14-16-24)11-6-12-25-18-8-3-2-7-17(18)22-21(25)26/h2-5,7-10H,6,11-16H2,1H3,(H,22,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair