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BDBM295685 US8242104, Compound 549

SMILES: CC(C)n1ncnc1-c1cn2CCOc3cc(OC(C4CC4)C(N)=O)ccc3-c2n1

InChI Key:

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 295685   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha


(Homo sapiens (Human))
BDBM295685
PNG
(US8242104, Compound 549)
Show SMILES CC(C)n1ncnc1-c1cn2CCOc3cc(OC(C4CC4)C(N)=O)ccc3-c2n1 |w:18.23|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.560n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent




US Patent US10112932 (2018)


BindingDB Entry DOI: 10.7270/Q2JQ132B
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform


(Homo sapiens (Human))
BDBM295685
PNG
(US8242104, Compound 549)
Show SMILES CC(C)n1ncnc1-c1cn2CCOc3cc(OC(C4CC4)C(N)=O)ccc3-c2n1 |w:18.23|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.70n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent




US Patent US10112932 (2018)


BindingDB Entry DOI: 10.7270/Q2JQ132B
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha


(Homo sapiens (Human))
BDBM295685
PNG
(US8242104, Compound 549)
Show SMILES CC(C)n1ncnc1-c1cn2CCOc3cc(OC(C4CC4)C(N)=O)ccc3-c2n1 |w:18.23|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
5.66n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent




US Patent US10112932 (2018)


BindingDB Entry DOI: 10.7270/Q2JQ132B
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform


(Homo sapiens (Human))
BDBM295685
PNG
(US8242104, Compound 549)
Show SMILES CC(C)n1ncnc1-c1cn2CCOc3cc(OC(C4CC4)C(N)=O)ccc3-c2n1 |w:18.23|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9.41n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent




US Patent US10112932 (2018)


BindingDB Entry DOI: 10.7270/Q2JQ132B
More data for this
Ligand-Target Pair