BDBM296082 2-[3-fluoro-4-(methyl-phenyl-amino)- phenoxy]-pyrido[3,4-d]pyrimidin-4-ol::US10112940, Example 10::US10202381, Example 10::US10208039, Example 10::US10611763, Example 10::US10815234, Example 10

SMILES: CN(c1ccccc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1F

InChI Key: InChIKey=YKNIDCVIHXRDHC-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296082 (2-[3-fluoro-4-(methyl-phenyl-amino)- phenoxy]-pyri...) Show SMILES CN(c1ccccc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1F Show InChI InChI=1S/C20H15FN4O2/c1-25(13-5-3-2-4-6-13)18-8-7-14(11-16(18)21)27-20-23-17-12-22-10-9-15(17)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296082 (2-[3-fluoro-4-(methyl-phenyl-amino)- phenoxy]-pyri...) Show SMILES CN(c1ccccc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1F Show InChI InChI=1S/C20H15FN4O2/c1-25(13-5-3-2-4-6-13)18-8-7-14(11-16(18)21)27-20-23-17-12-22-10-9-15(17)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (JMJD2C)(2-372) (Homo sapiens (Human))	BDBM296082 (2-[3-fluoro-4-(methyl-phenyl-amino)- phenoxy]-pyri...) Show SMILES CN(c1ccccc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1F Show InChI InChI=1S/C20H15FN4O2/c1-25(13-5-3-2-4-6-13)18-8-7-14(11-16(18)21)27-20-23-17-12-22-10-9-15(17)19(26)24-20/h2-12H,1H3,(H,23,24,26)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296082 (2-[3-fluoro-4-(methyl-phenyl-amino)- phenoxy]-pyri...) Show SMILES CN(c1ccccc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1F Show InChI InChI=1S/C20H15FN4O2/c1-25(13-5-3-2-4-6-13)18-8-7-14(11-16(18)21)27-20-23-17-12-22-10-9-15(17)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296082 (2-[3-fluoro-4-(methyl-phenyl-amino)- phenoxy]-pyri...) Show SMILES CN(c1ccccc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1F Show InChI InChI=1S/C20H15FN4O2/c1-25(13-5-3-2-4-6-13)18-8-7-14(11-16(18)21)27-20-23-17-12-22-10-9-15(17)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair