null

SMILES: CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(CN2CCN(C)CC2)c1

InChI Key: InChIKey=HIEXVOBPEWWGJY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296114 (2-(4-{methyl-[3-(4-methyl-piperazin-1- ylmethyl)-p...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(CN2CCN(C)CC2)c1 Show InChI InChI=1S/C26H28N6O2/c1-30-12-14-32(15-13-30)18-19-4-3-5-21(16-19)31(2)20-6-8-22(9-7-20)34-26-28-24-17-27-11-10-23(24)25(33)29-26/h3-11,16-17H,12-15,18H2,1-2H3,(H,28,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296114 (2-(4-{methyl-[3-(4-methyl-piperazin-1- ylmethyl)-p...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(CN2CCN(C)CC2)c1 Show InChI InChI=1S/C26H28N6O2/c1-30-12-14-32(15-13-30)18-19-4-3-5-21(16-19)31(2)20-6-8-22(9-7-20)34-26-28-24-17-27-11-10-23(24)25(33)29-26/h3-11,16-17H,12-15,18H2,1-2H3,(H,28,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C [2-372] (Homo sapiens (Human))	BDBM296114 (2-(4-{methyl-[3-(4-methyl-piperazin-1- ylmethyl)-p...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(CN2CCN(C)CC2)c1 Show InChI InChI=1S/C26H28N6O2/c1-30-12-14-32(15-13-30)18-19-4-3-5-21(16-19)31(2)20-6-8-22(9-7-20)34-26-28-24-17-27-11-10-23(24)25(33)29-26/h3-11,16-17H,12-15,18H2,1-2H3,(H,28,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296114 (2-(4-{methyl-[3-(4-methyl-piperazin-1- ylmethyl)-p...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(CN2CCN(C)CC2)c1 Show InChI InChI=1S/C26H28N6O2/c1-30-12-14-32(15-13-30)18-19-4-3-5-21(16-19)31(2)20-6-8-22(9-7-20)34-26-28-24-17-27-11-10-23(24)25(33)29-26/h3-11,16-17H,12-15,18H2,1-2H3,(H,28,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296114 (2-(4-{methyl-[3-(4-methyl-piperazin-1- ylmethyl)-p...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(CN2CCN(C)CC2)c1 Show InChI InChI=1S/C26H28N6O2/c1-30-12-14-32(15-13-30)18-19-4-3-5-21(16-19)31(2)20-6-8-22(9-7-20)34-26-28-24-17-27-11-10-23(24)25(33)29-26/h3-11,16-17H,12-15,18H2,1-2H3,(H,28,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair