BDBM296127 2-[4-[methyl-[(1S)-1- phenylethyl]amino]phenoxy]pyrido[3,4- d]pyrimidin-4-ol::US10112940, Example 51::US10202381, Example 51::US10208039, Example 51::US10611763, Example 51::US10815234, Example 51

SMILES: C[C@H](N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccccc1

InChI Key: InChIKey=UCLABKYGVIGHCE-HNNXBMFYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296127 (2-[4-[methyl-[(1S)-1- phenylethyl]amino]phenoxy]py...) Show SMILES C[C@H](N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccccc1 |r| Show InChI InChI=1S/C22H20N4O2/c1-15(16-6-4-3-5-7-16)26(2)17-8-10-18(11-9-17)28-22-24-20-14-23-13-12-19(20)21(27)25-22/h3-15H,1-2H3,(H,24,25,27)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296127 (2-[4-[methyl-[(1S)-1- phenylethyl]amino]phenoxy]py...) Show SMILES C[C@H](N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccccc1 |r| Show InChI InChI=1S/C22H20N4O2/c1-15(16-6-4-3-5-7-16)26(2)17-8-10-18(11-9-17)28-22-24-20-14-23-13-12-19(20)21(27)25-22/h3-15H,1-2H3,(H,24,25,27)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C [2-372] (Homo sapiens (Human))	BDBM296127 (2-[4-[methyl-[(1S)-1- phenylethyl]amino]phenoxy]py...) Show SMILES C[C@H](N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccccc1 |r| Show InChI InChI=1S/C22H20N4O2/c1-15(16-6-4-3-5-7-16)26(2)17-8-10-18(11-9-17)28-22-24-20-14-23-13-12-19(20)21(27)25-22/h3-15H,1-2H3,(H,24,25,27)/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296127 (2-[4-[methyl-[(1S)-1- phenylethyl]amino]phenoxy]py...) Show SMILES C[C@H](N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccccc1 |r| Show InChI InChI=1S/C22H20N4O2/c1-15(16-6-4-3-5-7-16)26(2)17-8-10-18(11-9-17)28-22-24-20-14-23-13-12-19(20)21(27)25-22/h3-15H,1-2H3,(H,24,25,27)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296127 (2-[4-[methyl-[(1S)-1- phenylethyl]amino]phenoxy]py...) Show SMILES C[C@H](N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccccc1 |r| Show InChI InChI=1S/C22H20N4O2/c1-15(16-6-4-3-5-7-16)26(2)17-8-10-18(11-9-17)28-22-24-20-14-23-13-12-19(20)21(27)25-22/h3-15H,1-2H3,(H,24,25,27)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair