null

SMILES: Oc1nc(Oc2ccc(cc2)N2CCC(C2)c2ccccc2)nc2cnccc12

InChI Key: InChIKey=GVRPQGJEOVBHLR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296130 (2-[4-(3-phenylpyrrolidin-1- yl)phenoxy]pyrido[3,4-...) Show SMILES Oc1nc(Oc2ccc(cc2)N2CCC(C2)c2ccccc2)nc2cnccc12 Show InChI InChI=1S/C23H20N4O2/c28-22-20-10-12-24-14-21(20)25-23(26-22)29-19-8-6-18(7-9-19)27-13-11-17(15-27)16-4-2-1-3-5-16/h1-10,12,14,17H,11,13,15H2,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296130 (2-[4-(3-phenylpyrrolidin-1- yl)phenoxy]pyrido[3,4-...) Show SMILES Oc1nc(Oc2ccc(cc2)N2CCC(C2)c2ccccc2)nc2cnccc12 Show InChI InChI=1S/C23H20N4O2/c28-22-20-10-12-24-14-21(20)25-23(26-22)29-19-8-6-18(7-9-19)27-13-11-17(15-27)16-4-2-1-3-5-16/h1-10,12,14,17H,11,13,15H2,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C [2-372] (Homo sapiens (Human))	BDBM296130 (2-[4-(3-phenylpyrrolidin-1- yl)phenoxy]pyrido[3,4-...) Show SMILES Oc1nc(Oc2ccc(cc2)N2CCC(C2)c2ccccc2)nc2cnccc12 Show InChI InChI=1S/C23H20N4O2/c28-22-20-10-12-24-14-21(20)25-23(26-22)29-19-8-6-18(7-9-19)27-13-11-17(15-27)16-4-2-1-3-5-16/h1-10,12,14,17H,11,13,15H2,(H,25,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296130 (2-[4-(3-phenylpyrrolidin-1- yl)phenoxy]pyrido[3,4-...) Show SMILES Oc1nc(Oc2ccc(cc2)N2CCC(C2)c2ccccc2)nc2cnccc12 Show InChI InChI=1S/C23H20N4O2/c28-22-20-10-12-24-14-21(20)25-23(26-22)29-19-8-6-18(7-9-19)27-13-11-17(15-27)16-4-2-1-3-5-16/h1-10,12,14,17H,11,13,15H2,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296130 (2-[4-(3-phenylpyrrolidin-1- yl)phenoxy]pyrido[3,4-...) Show SMILES Oc1nc(Oc2ccc(cc2)N2CCC(C2)c2ccccc2)nc2cnccc12 Show InChI InChI=1S/C23H20N4O2/c28-22-20-10-12-24-14-21(20)25-23(26-22)29-19-8-6-18(7-9-19)27-13-11-17(15-27)16-4-2-1-3-5-16/h1-10,12,14,17H,11,13,15H2,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair