null

SMILES: CCc1ccc(cc1N1CCN(C)CC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1

InChI Key: InChIKey=HFKUHUUSLPEHMF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296136 (2-[4-[4-ethyl-N-methyl-3-(4- methylpiperazin-1- yl...) Show SMILES CCc1ccc(cc1N1CCN(C)CC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H30N6O2/c1-4-19-5-6-21(17-25(19)33-15-13-31(2)14-16-33)32(3)20-7-9-22(10-8-20)35-27-29-24-18-28-12-11-23(24)26(34)30-27/h5-12,17-18H,4,13-16H2,1-3H3,(H,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296136 (2-[4-[4-ethyl-N-methyl-3-(4- methylpiperazin-1- yl...) Show SMILES CCc1ccc(cc1N1CCN(C)CC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H30N6O2/c1-4-19-5-6-21(17-25(19)33-15-13-31(2)14-16-33)32(3)20-7-9-22(10-8-20)35-27-29-24-18-28-12-11-23(24)26(34)30-27/h5-12,17-18H,4,13-16H2,1-3H3,(H,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C [2-372] (Homo sapiens (Human))	BDBM296136 (2-[4-[4-ethyl-N-methyl-3-(4- methylpiperazin-1- yl...) Show SMILES CCc1ccc(cc1N1CCN(C)CC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H30N6O2/c1-4-19-5-6-21(17-25(19)33-15-13-31(2)14-16-33)32(3)20-7-9-22(10-8-20)35-27-29-24-18-28-12-11-23(24)26(34)30-27/h5-12,17-18H,4,13-16H2,1-3H3,(H,29,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296136 (2-[4-[4-ethyl-N-methyl-3-(4- methylpiperazin-1- yl...) Show SMILES CCc1ccc(cc1N1CCN(C)CC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H30N6O2/c1-4-19-5-6-21(17-25(19)33-15-13-31(2)14-16-33)32(3)20-7-9-22(10-8-20)35-27-29-24-18-28-12-11-23(24)26(34)30-27/h5-12,17-18H,4,13-16H2,1-3H3,(H,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296136 (2-[4-[4-ethyl-N-methyl-3-(4- methylpiperazin-1- yl...) Show SMILES CCc1ccc(cc1N1CCN(C)CC1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H30N6O2/c1-4-19-5-6-21(17-25(19)33-15-13-31(2)14-16-33)32(3)20-7-9-22(10-8-20)35-27-29-24-18-28-12-11-23(24)26(34)30-27/h5-12,17-18H,4,13-16H2,1-3H3,(H,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair