BDBM296152 2-[4-[4-(cyclopropylmethyl)-N- methylanilino]phenoxy]pyrido[3,4- d]pyrimidin-4-ol::US10112940, Example 76::US10202381, Example 76::US10208039, Example 76::US10611763, Example 76::US10815234, Example 76

SMILES: CN(c1ccc(CC2CC2)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1

InChI Key: InChIKey=BRPMHVOFOJZGFY-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296152 (2-[4-[4-(cyclopropylmethyl)-N- methylanilino]pheno...) Show SMILES CN(c1ccc(CC2CC2)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C24H22N4O2/c1-28(18-6-4-17(5-7-18)14-16-2-3-16)19-8-10-20(11-9-19)30-24-26-22-15-25-13-12-21(22)23(29)27-24/h4-13,15-16H,2-3,14H2,1H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296152 (2-[4-[4-(cyclopropylmethyl)-N- methylanilino]pheno...) Show SMILES CN(c1ccc(CC2CC2)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C24H22N4O2/c1-28(18-6-4-17(5-7-18)14-16-2-3-16)19-8-10-20(11-9-19)30-24-26-22-15-25-13-12-21(22)23(29)27-24/h4-13,15-16H,2-3,14H2,1H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (JMJD2C)(2-372) (Homo sapiens (Human))	BDBM296152 (2-[4-[4-(cyclopropylmethyl)-N- methylanilino]pheno...) Show SMILES CN(c1ccc(CC2CC2)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C24H22N4O2/c1-28(18-6-4-17(5-7-18)14-16-2-3-16)19-8-10-20(11-9-19)30-24-26-22-15-25-13-12-21(22)23(29)27-24/h4-13,15-16H,2-3,14H2,1H3,(H,26,27,29)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296152 (2-[4-[4-(cyclopropylmethyl)-N- methylanilino]pheno...) Show SMILES CN(c1ccc(CC2CC2)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C24H22N4O2/c1-28(18-6-4-17(5-7-18)14-16-2-3-16)19-8-10-20(11-9-19)30-24-26-22-15-25-13-12-21(22)23(29)27-24/h4-13,15-16H,2-3,14H2,1H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296152 (2-[4-[4-(cyclopropylmethyl)-N- methylanilino]pheno...) Show SMILES CN(c1ccc(CC2CC2)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C24H22N4O2/c1-28(18-6-4-17(5-7-18)14-16-2-3-16)19-8-10-20(11-9-19)30-24-26-22-15-25-13-12-21(22)23(29)27-24/h4-13,15-16H,2-3,14H2,1H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair