BDBM296160 2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- d]pyrimidin-4-ol::US10112940, Example 83::US10202381, Example 83::US10208039, Example 83::US10611763, Example 83::US10815234, Example 83

SMILES: CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1

InChI Key: InChIKey=LEEOBDATXTXUKR-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296160 (2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- ...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1 Show InChI InChI=1S/C22H20N4O2/c1-14-4-5-17(12-15(14)2)26(3)16-6-8-18(9-7-16)28-22-24-20-13-23-11-10-19(20)21(27)25-22/h4-13H,1-3H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296160 (2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- ...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1 Show InChI InChI=1S/C22H20N4O2/c1-14-4-5-17(12-15(14)2)26(3)16-6-8-18(9-7-16)28-22-24-20-13-23-11-10-19(20)21(27)25-22/h4-13H,1-3H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (JMJD2C)(2-372) (Homo sapiens (Human))	BDBM296160 (2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- ...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1 Show InChI InChI=1S/C22H20N4O2/c1-14-4-5-17(12-15(14)2)26(3)16-6-8-18(9-7-16)28-22-24-20-13-23-11-10-19(20)21(27)25-22/h4-13H,1-3H3,(H,24,25,27)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296160 (2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- ...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1 Show InChI InChI=1S/C22H20N4O2/c1-14-4-5-17(12-15(14)2)26(3)16-6-8-18(9-7-16)28-22-24-20-13-23-11-10-19(20)21(27)25-22/h4-13H,1-3H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296160 (2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- ...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1 Show InChI InChI=1S/C22H20N4O2/c1-14-4-5-17(12-15(14)2)26(3)16-6-8-18(9-7-16)28-22-24-20-13-23-11-10-19(20)21(27)25-22/h4-13H,1-3H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair