BDBM296172 2-[4-(3-chloro-N- methylanilino)phenoxy]pyrido[3,4- d]pyrimidin-4-ol::US10112940, Example 95::US10202381, Example 95::US10208039, Example 95::US10611763, Example 95::US10815234, Example 95

SMILES: CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(Cl)c1

InChI Key: InChIKey=WPXNVAPMYMQGFE-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296172 (2-[4-(3-chloro-N- methylanilino)phenoxy]pyrido[3,4...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C20H15ClN4O2/c1-25(15-4-2-3-13(21)11-15)14-5-7-16(8-6-14)27-20-23-18-12-22-10-9-17(18)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296172 (2-[4-(3-chloro-N- methylanilino)phenoxy]pyrido[3,4...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C20H15ClN4O2/c1-25(15-4-2-3-13(21)11-15)14-5-7-16(8-6-14)27-20-23-18-12-22-10-9-17(18)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C [2-372] (Homo sapiens (Human))	BDBM296172 (2-[4-(3-chloro-N- methylanilino)phenoxy]pyrido[3,4...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C20H15ClN4O2/c1-25(15-4-2-3-13(21)11-15)14-5-7-16(8-6-14)27-20-23-18-12-22-10-9-17(18)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296172 (2-[4-(3-chloro-N- methylanilino)phenoxy]pyrido[3,4...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C20H15ClN4O2/c1-25(15-4-2-3-13(21)11-15)14-5-7-16(8-6-14)27-20-23-18-12-22-10-9-17(18)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296172 (2-[4-(3-chloro-N- methylanilino)phenoxy]pyrido[3,4...) Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1cccc(Cl)c1 Show InChI InChI=1S/C20H15ClN4O2/c1-25(15-4-2-3-13(21)11-15)14-5-7-16(8-6-14)27-20-23-18-12-22-10-9-17(18)19(26)24-20/h2-12H,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair