BDBM29665 (9-Oxo-9H-acridin-10-yl)-acetic acid (2,5-dimethyl-1-p-tolyl-1H-pyrrol-3-ylmethylene)-hydrazide::MLS000566526::N-[[2,5-dimethyl-1-(4-methylphenyl)-3-pyrrolyl]methylideneamino]-2-(9-oxo-10-acridinyl)acetamide::N-[[2,5-dimethyl-1-(4-methylphenyl)pyrrol-3-yl]methylideneamino]-2-(9-oxidanylideneacridin-10-yl)ethanamide::N-[[2,5-dimethyl-1-(4-methylphenyl)pyrrol-3-yl]methylideneamino]-2-(9-oxoacridin-10-yl)acetamide::N-[[2,5-dimethyl-1-(p-tolyl)pyrrol-3-yl]methyleneamino]-2-(9-ketoacridin-10-yl)acetamide::SMR000175922::cid_3116773

SMILES: Cc1cc(C=NNC(=O)Cn2c3ccccc3c(=O)c3ccccc23)c(C)n1-c1ccc(C)cc1

InChI Key: InChIKey=FISFZWCOEIHCKY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29665 ((9-Oxo-9H-acridin-10-yl)-acetic acid (2,5-dimethyl...) Show SMILES Cc1cc(C=NNC(=O)Cn2c3ccccc3c(=O)c3ccccc23)c(C)n1-c1ccc(C)cc1 |w:5.5| Show InChI InChI=1S/C29H26N4O2/c1-19-12-14-23(15-13-19)33-20(2)16-22(21(33)3)17-30-31-28(34)18-32-26-10-6-4-8-24(26)29(35)25-9-5-7-11-27(25)32/h4-17H,18H2,1-3H3,(H,31,34)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29665 ((9-Oxo-9H-acridin-10-yl)-acetic acid (2,5-dimethyl...) Show SMILES Cc1cc(C=NNC(=O)Cn2c3ccccc3c(=O)c3ccccc23)c(C)n1-c1ccc(C)cc1 |w:5.5| Show InChI InChI=1S/C29H26N4O2/c1-19-12-14-23(15-13-19)33-20(2)16-22(21(33)3)17-30-31-28(34)18-32-26-10-6-4-8-24(26)29(35)25-9-5-7-11-27(25)32/h4-17H,18H2,1-3H3,(H,31,34)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair