BDBM29683 MLS000666106::N-[3-cyano-1-(2-furanylmethyl)-5-oxo-2-dipyrido[1,2-d:3',4'-f]pyrimidinylidene]-2-furancarboxamide::N-[3-cyano-1-(2-furfuryl)-5-keto-dipyrido[1,2-d:3',4'-f]pyrimidin-2-ylidene]-2-furamide::N-[3-cyano-1-(2-furylmethyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]-2-furamide::N-[3-cyano-1-(furan-2-ylmethyl)-5-oxidanylidene-dipyrido[1,2-d:3',4'-f]pyrimidin-2-ylidene]furan-2-carboxamide::N-[3-cyano-1-(furan-2-ylmethyl)-5-oxodipyrido[1,2-d:3',4'-f]pyrimidin-2-ylidene]furan-2-carboxamide::SMR000271415::cid_1279881

SMILES: O=C(\N=c1/c(cc2c(nc3ccccn3c2=O)n1Cc1ccco1)C#N)c1ccco1

InChI Key: InChIKey=YTKDDTDTKZGUHJ-NCELDCMTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29683 (MLS000666106 | N-[3-cyano-1-(2-furanylmethyl)-5-ox...) Show SMILES O=C(\N=c1/c(cc2c(nc3ccccn3c2=O)n1Cc1ccco1)C#N)c1ccco1 Show InChI InChI=1S/C22H13N5O4/c23-12-14-11-16-20(24-18-7-1-2-8-26(18)22(16)29)27(13-15-5-3-9-30-15)19(14)25-21(28)17-6-4-10-31-17/h1-11H,13H2/b25-19+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.61E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29683 (MLS000666106 | N-[3-cyano-1-(2-furanylmethyl)-5-ox...) Show SMILES O=C(\N=c1/c(cc2c(nc3ccccn3c2=O)n1Cc1ccco1)C#N)c1ccco1 Show InChI InChI=1S/C22H13N5O4/c23-12-14-11-16-20(24-18-7-1-2-8-26(18)22(16)29)27(13-15-5-3-9-30-15)19(14)25-21(28)17-6-4-10-31-17/h1-11H,13H2/b25-19+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.61E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair