BDBM298287 US10123984, Example 2G::US10744104, Example 2G

SMILES: CC(C)OC(=O)C(=O)N[C@@H](C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1

InChI Key: InChIKey=RVMXFNOVEPCUIG-RTBURBONSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM298287 (US10123984, Example 2G | US10744104, Example 2G) Show SMILES CC(C)OC(=O)C(=O)N[C@@H](C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C22H24ClNO6/c1-13(2)30-22(29)20(26)24-18(12-19(25)21(27)28)10-14-6-8-15(9-7-14)16-4-3-5-17(23)11-16/h3-9,11,13,18-19,25H,10,12H2,1-2H3,(H,24,26)(H,27,28)/t18-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Biopharma R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10744104 (2020)
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM298287 (US10123984, Example 2G | US10744104, Example 2G) Show SMILES CC(C)OC(=O)C(=O)N[C@@H](C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C22H24ClNO6/c1-13(2)30-22(29)20(26)24-18(12-19(25)21(27)28)10-14-6-8-15(9-7-14)16-4-3-5-17(23)11-16/h3-9,11,13,18-19,25H,10,12H2,1-2H3,(H,24,26)(H,27,28)/t18-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
					More data for this Ligand-Target Pair