null

SMILES: CCOC(=O)[C@@H](CN(Cc1ccc(Br)cc1)NC(=O)C(=O)OCC)OC(=O)C(=O)OCC

InChI Key: InChIKey=BRKMRNSILIJOQW-OAHLLOKOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 298322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM298322 (US10123984, Example 14A | US10123984, Example 14C ...) Show SMILES CCOC(=O)[C@@H](CN(Cc1ccc(Br)cc1)NC(=O)C(=O)OCC)OC(=O)C(=O)OCC |r| Show InChI InChI=1S/C20H25BrN2O9/c1-4-29-17(25)15(32-20(28)19(27)31-6-3)12-23(22-16(24)18(26)30-5-2)11-13-7-9-14(21)10-8-13/h7-10,15H,4-6,11-12H2,1-3H3,(H,22,24)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM298322 (US10123984, Example 14A | US10123984, Example 14C ...) Show SMILES CCOC(=O)[C@@H](CN(Cc1ccc(Br)cc1)NC(=O)C(=O)OCC)OC(=O)C(=O)OCC |r| Show InChI InChI=1S/C20H25BrN2O9/c1-4-29-17(25)15(32-20(28)19(27)31-6-3)12-23(22-16(24)18(26)30-5-2)11-13-7-9-14(21)10-8-13/h7-10,15H,4-6,11-12H2,1-3H3,(H,22,24)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM298322 (US10123984, Example 14A | US10123984, Example 14C ...) Show SMILES CCOC(=O)[C@@H](CN(Cc1ccc(Br)cc1)NC(=O)C(=O)OCC)OC(=O)C(=O)OCC |r| Show InChI InChI=1S/C20H25BrN2O9/c1-4-29-17(25)15(32-20(28)19(27)31-6-3)12-23(22-16(24)18(26)30-5-2)11-13-7-9-14(21)10-8-13/h7-10,15H,4-6,11-12H2,1-3H3,(H,22,24)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
					More data for this Ligand-Target Pair