BDBM298356 (S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzoyl)-4-(methythio)pyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::US10125097, Example 5::US10611727, Example 5

SMILES: COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@H](C[C@H]1C(=O)N1CCC[C@H]1C#N)SC

InChI Key: InChIKey=AXAQGOMOKDBQGF-FKBYEOEOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase-like (Human)	BDBM298356 ((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@H](C[C@H]1C(=O)N1CCC[C@H]1C#N)SC |r| Show InChI InChI=1S/C27H31N3O5S/c1-33-23-12-19(13-24(34-2)25(23)35-17-18-8-5-4-6-9-18)26(31)30-16-21(36-3)14-22(30)27(32)29-11-7-10-20(29)15-28/h4-6,8-9,12-13,20-22H,7,10-11,14,16-17H2,1-3H3/t20-,21-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITAT DE BARCELONA; FUNACIÓ INSTITUT DE RECERCA BIOMÉDICA; IPROTEOS S.L. US Patent					Assay Description POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...				US Patent US10611727 (2020)
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM298356 ((S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzo...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@H](C[C@H]1C(=O)N1CCC[C@H]1C#N)SC |r| Show InChI InChI=1S/C27H31N3O5S/c1-33-23-12-19(13-24(34-2)25(23)35-17-18-8-5-4-6-9-18)26(31)30-16-21(36-3)14-22(30)27(32)29-11-7-10-20(29)15-28/h4-6,8-9,12-13,20-22H,7,10-11,14,16-17H2,1-3H3/t20-,21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
UNIVERSITAT DE BARCELONA; FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA); IPROTEOS S.L. US Patent					Assay Description POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...				US Patent US10125097 (2018) BindingDB Entry DOI: 10.7270/Q22J6DX3
					More data for this Ligand-Target Pair