BDBM29845 N-(Pyridin-2-yl) arylsulfonamide, 5

SMILES: Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(=O)N2CCSCC2)n1

InChI Key: InChIKey=SSCXJKIURZDFOK-UHFFFAOYSA-N

Data: 1 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29845 (N-(Pyridin-2-yl) arylsulfonamide, 5) Show SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(=O)N2CCSCC2)n1 Show InChI InChI=1S/C18H20ClN3O3S2/c1-13-15(19)5-3-6-16(13)27(24,25)21-17-7-2-4-14(20-17)12-18(23)22-8-10-26-11-9-22/h2-7H,8-12H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair