BDBM298833 US10125118, Example 239::US10947215, Example 239

SMILES: CN1CCC(Cc2ccc(cc2)-c2ccc(CO[C@H]3CCC[C@@H]3NC(=O)c3cc(cnc3N)-c3cnn(C)c3)cc2)CC1

InChI Key: InChIKey=NRXCOTQAIVGUCM-LQJZCPKCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
recombinant proteins of human c-MER and AXL catalytic domains (Homo sapiens (Human))	BDBM298833 (US10125118, Example 239 | US10947215, Example 239) Show SMILES CN1CCC(Cc2ccc(cc2)-c2ccc(CO[C@H]3CCC[C@@H]3NC(=O)c3cc(cnc3N)-c3cnn(C)c3)cc2)CC1 |r| Show InChI InChI=1S/C35H42N6O2/c1-40-16-14-25(15-17-40)18-24-6-10-27(11-7-24)28-12-8-26(9-13-28)23-43-33-5-3-4-32(33)39-35(42)31-19-29(20-37-34(31)36)30-21-38-41(2)22-30/h6-13,19-22,25,32-33H,3-5,14-18,23H2,1-2H3,(H2,36,37)(H,39,42)/t32-,33-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Dong-A Socio Holdings Co., Ltd. US Patent					Assay Description For the SAR (structure-activity relationship) and compound screening, LanthaScreen™ TR-FRET (Time-Resolved fluorescence energy transfer) assay was em...				US Patent US10947215 (2021)
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM298833 (US10125118, Example 239 | US10947215, Example 239) Show SMILES CN1CCC(Cc2ccc(cc2)-c2ccc(CO[C@H]3CCC[C@@H]3NC(=O)c3cc(cnc3N)-c3cnn(C)c3)cc2)CC1 |r| Show InChI InChI=1S/C35H42N6O2/c1-40-16-14-25(15-17-40)18-24-6-10-27(11-7-24)28-12-8-26(9-13-28)23-43-33-5-3-4-32(33)39-35(42)31-19-29(20-37-34(31)36)30-21-38-41(2)22-30/h6-13,19-22,25,32-33H,3-5,14-18,23H2,1-2H3,(H2,36,37)(H,39,42)/t32-,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Dong-A Socio Holdings Co., Ltd. US Patent					Assay Description TBD				US Patent US10125118 (2018) BindingDB Entry DOI: 10.7270/Q2JM2CQH
					More data for this Ligand-Target Pair