BindingDB logo
myBDB logout

null

SMILES: CCOC(=O)[C@H](CO)C[C@@H](Cc1ccc(cc1)-c1cc(Cl)ccc1F)NB(C)O

InChI Key: InChIKey=VDXSNKABWFMDLM-FUHWJXTLSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299668   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM299668
PNG
((2S,4S)-2-[(2-Aminoacetylamino)methyl]-5-(5′...)
Show SMILES CCOC(=O)[C@H](CO)C[C@@H](Cc1ccc(cc1)-c1cc(Cl)ccc1F)NB(C)O |r|
Show InChI InChI=1S/C21H26BClFNO4/c1-3-29-21(27)16(13-26)11-18(25-22(2)28)10-14-4-6-15(7-5-14)19-12-17(23)8-9-20(19)24/h4-9,12,16,18,25-26,28H,3,10-11,13H2,1-2H3/t16-,18+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<1n/an/an/an/an/an/an/an/a



Theravence Biopharma R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...

US Patent US9593110 (2017)


BindingDB Entry DOI: 10.7270/Q2MC9224
More data for this
Ligand-Target Pair