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SMILES:

InChI Key: InChIKey=STESRDYXGDNABU-WZONZLPQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300348   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Homo sapiens (Human))
BDBM300348
PNG
(US9593110, 16-24)
Show InChI InChI=1S/C27H22Cl2FN3O4/c28-17-9-10-22(30)20(12-17)16-7-5-15(6-8-16)11-18(13-23(31)27(35)36)32-26(34)25-14-24(33-37-25)19-3-1-2-4-21(19)29/h1-10,12,14,18,23H,11,13,31H2,(H,32,34)(H,35,36)/t18-,23-/m1/s1
PDB

KEGG

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PC cid
PC sid
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US Patent
<1n/an/an/an/an/an/an/an/a



Theravence Biopharma R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...


US Patent US9593110 (2017)


BindingDB Entry DOI: 10.7270/Q2MC9224
More data for this
Ligand-Target Pair