BDBM300349 US9593110, 16-25

SMILES:

InChI Key: InChIKey=KRZJZRLBSHPMQU-YLJYHZDGSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM300349 (US9593110, 16-25) Show SMILES Show InChI InChI=1S/C24H20Cl2FN5O3/c25-15-5-6-19(27)18(10-15)14-3-1-13(2-4-14)9-17(12-20(28)24(34)35)29-23(33)22-30-21-11-16(26)7-8-32(21)31-22/h1-8,10-11,17,20H,9,12,28H2,(H,29,33)(H,34,35)/t17-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravence Biopharma R&D IP, LLC US Patent					Assay Description Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...				US Patent US9593110 (2017) BindingDB Entry DOI: 10.7270/Q2MC9224
					More data for this Ligand-Target Pair