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SMILES: CN1CCN(CC(=O)Nc2cc(ccc2C#N)C(=O)Nc2nnc(s2)-c2ccccc2)CC1

InChI Key: InChIKey=VWIDLKSSNAOYJK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Homo sapiens (Human))	BDBM300604 (4-cyano-3-{[(4-methylpiperazin-1-yl)acetyl]amino}-...) Show SMILES CN1CCN(CC(=O)Nc2cc(ccc2C#N)C(=O)Nc2nnc(s2)-c2ccccc2)CC1 |$;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H23N7O2S/c1-29-9-11-30(12-10-29)15-20(31)25-19-13-17(7-8-18(19)14-24)21(32)26-23-28-27-22(33-23)16-5-3-2-4-6-16/h2-8,13H,9-12,15H2,1H3,(H,25,31)(H,26,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300604 (4-cyano-3-{[(4-methylpiperazin-1-yl)acetyl]amino}-...) Show SMILES CN1CCN(CC(=O)Nc2cc(ccc2C#N)C(=O)Nc2nnc(s2)-c2ccccc2)CC1 |$;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H23N7O2S/c1-29-9-11-30(12-10-29)15-20(31)25-19-13-17(7-8-18(19)14-24)21(32)26-23-28-27-22(33-23)16-5-3-2-4-6-16/h2-8,13H,9-12,15H2,1H3,(H,25,31)(H,26,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair