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SMILES: OCC(CC(Cc1ccccc1)NC(=O)c1cn(O)nn1)C(O)=O

InChI Key: InChIKey=ADKWGSHMRHHABB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300711   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM300711
PNG
(US10130642, Example 4-7)
Show SMILES OCC(CC(Cc1ccccc1)NC(=O)c1cn(O)nn1)C(O)=O
Show InChI InChI=1S/C15H18N4O5/c20-9-11(15(22)23)7-12(6-10-4-2-1-3-5-10)16-14(21)13-8-19(24)18-17-13/h1-5,8,11-12,20,24H,6-7,9H2,(H,16,21)(H,22,23)
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US Patent
<1n/an/an/an/an/an/an/an/a



THERAVANCE BIOPHARMA R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...

US Patent US10130642 (2018)


BindingDB Entry DOI: 10.7270/Q29Z96ZH
More data for this
Ligand-Target Pair