BDBM300903 (2S, 3R)-3-((R or S)-2-(1-(2, 5-bis (trifluoromethyl) benzyl) azetidin-3-yl)-2, 3, 4, 5-tetrahydrobenzo[b]oxepin-8-yl)-3-cyclopropyl-2-methylpropanoic acid::US10131651, Example 3

SMILES: C[C@@H]([C@@H](C1CC1)c1ccc2CCC[C@H](Oc2c1)C1CN(Cc2cc(ccc2C(F)(F)F)C(F)(F)F)C1)C(O)=O

InChI Key: InChIKey=BAKXTOWRITUZSO-DTNWAODDSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM300903 ((2S, 3R)-3-((R or S)-2-(1-(2, 5-bis (trifluorometh...) Show SMILES C[C@@H]([C@@H](C1CC1)c1ccc2CCC[C@H](Oc2c1)C1CN(Cc2cc(ccc2C(F)(F)F)C(F)(F)F)C1)C(O)=O |r| Show InChI InChI=1S/C29H31F6NO3/c1-16(27(37)38)26(18-6-7-18)19-8-5-17-3-2-4-24(39-25(17)12-19)21-14-36(15-21)13-20-11-22(28(30,31)32)9-10-23(20)29(33,34)35/h5,8-12,16,18,21,24,26H,2-4,6-7,13-15H2,1H3,(H,37,38)/t16-,24-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The assay is performed in 384-well format. HEK cells stably expressing human GPR40 are plated at 15,000 cells per well in growth medium (DMEM/10% fet...				US Patent US10131651 (2018) BindingDB Entry DOI: 10.7270/Q2XP770F
					More data for this Ligand-Target Pair