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BDBM301767 ((S)-6-{(R)-7-Fluoro-4-[4-(2-methylthiazol-4-yl)phenoxy]-indan-1-yloxy}-2,3-dihydrobenzofuran-3-yl)-acetic acid methyl ester::US9597310, 57

SMILES: COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3c(F)ccc4Oc3ccc(cc3)-c3csc(C)n3)ccc12

InChI Key: InChIKey=RVHJUFBNZBUFGE-XHCCPWGMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301767   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM301767
PNG
(((S)-6-{(R)-7-Fluoro-4-[4-(2-methylthiazol-4-yl)ph...)
Show SMILES COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3c(F)ccc4Oc3ccc(cc3)-c3csc(C)n3)ccc12 |r|
Show InChI InChI=1S/C30H26FNO5S/c1-17-32-25(16-38-17)18-3-5-20(6-4-18)36-26-12-10-24(31)30-23(26)9-11-27(30)37-21-7-8-22-19(13-29(33)34-2)15-35-28(22)14-21/h3-8,10,12,14,16,19,27H,9,11,13,15H2,1-2H3/t19-,27-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 4n/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
IP1 accumulation measurements using the IPOne assay system 1321N1 cells stably expressing human GPR40 receptor (Euroscreen, Belgium) are seeded 24 h ...


US Patent US9597310 (2017)


BindingDB Entry DOI: 10.7270/Q2RX9F3W
More data for this
Ligand-Target Pair