BDBM301977 5-Fluoro-3-(4-(4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)butyl)-1H-indole::US9598401, Example 31

SMILES: Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3nccc(n3)C(F)(F)F)c2c1

InChI Key: InChIKey=GBLATCMJGSYEQR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301977 (5-Fluoro-3-(4-(4-(4-(trifluoromethyl)pyrimidin-2-y...) Show SMILES Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3nccc(n3)C(F)(F)F)c2c1 Show InChI InChI=1S/C21H23F4N5/c22-16-4-5-18-17(13-16)15(14-27-18)3-1-2-8-29-9-11-30(12-10-29)20-26-7-6-19(28-20)21(23,24)25/h4-7,13-14,27H,1-3,8-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair