BindingDB logo
myBDB logout

null

SMILES: FC(F)(F)c1ccnc(n1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1

InChI Key: InChIKey=APDZEZNZSICSHL-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301978   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM301978
PNG
(3-(4-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperaz...)
Show SMILES FC(F)(F)c1ccnc(n1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Show InChI InChI=1S/C22H23F3N6/c23-22(24,25)20-6-7-27-21(29-20)31-11-9-30(10-12-31)8-2-1-3-17-15-28-19-5-4-16(14-26)13-18(17)19/h4-7,13,15,28H,1-3,8-12H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 0.700n/an/an/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...

US Patent US9598401 (2017)


BindingDB Entry DOI: 10.7270/Q2GH9M1F
More data for this
Ligand-Target Pair