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BDBM301979 5-Fluoro-3-(3-(4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)propyl)-1H-indole::US9598401, Example 33

SMILES: Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3nccc(n3)C(F)(F)F)c2c1

InChI Key: InChIKey=MZBZVMLKIZAFMA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301979   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM301979
PNG
(5-Fluoro-3-(3-(4-(4-(trifluoromethyl)pyrimidin-2-y...)
Show SMILES Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3nccc(n3)C(F)(F)F)c2c1
Show InChI InChI=1S/C20H21F4N5/c21-15-3-4-17-16(12-15)14(13-26-17)2-1-7-28-8-10-29(11-9-28)19-25-6-5-18(27-19)20(22,23)24/h3-6,12-13,26H,1-2,7-11H2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
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UniChem
US Patent
 1n/an/an/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...

US Patent US9598401 (2017)


BindingDB Entry DOI: 10.7270/Q2GH9M1F
More data for this
Ligand-Target Pair