BDBM302362 6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,14][1,2,4]-triazin-4-amine dihydrochloride::US9598416, Example 8
SMILES: COc1cc(C)cc2cc(sc12)-c1c(COCCN)cn2ncnc(N)c12
InChI Key: InChIKey=NSZYKHCVXAXWHM-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM302362 (6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM302362 (6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM... | US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R | |||||||||||
More data for this Ligand-Target Pair |