BDBM302443 N5-Cyclopentyl-2-(3- fluorophenyl)-6,7- dihydropyrazolo[1,5-a] pyrazine-3,5(4H)- dicarboxamide::US9598423, Example 9

SMILES: NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)NC1CCCC1

InChI Key: InChIKey=DZAKDVZYMFUDPV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302443 (N5-Cyclopentyl-2-(3- fluorophenyl)-6,7- dihydropyr...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)NC1CCCC1 Show InChI InChI=1S/C19H22FN5O2/c20-13-5-3-4-12(10-13)17-16(18(21)26)15-11-24(8-9-25(15)23-17)19(27)22-14-6-1-2-7-14/h3-5,10,14H,1-2,6-9,11H2,(H2,21,26)(H,22,27)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM302443 (N5-Cyclopentyl-2-(3- fluorophenyl)-6,7- dihydropyr...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)NC1CCCC1 Show InChI InChI=1S/C19H22FN5O2/c20-13-5-3-4-12(10-13)17-16(18(21)26)15-11-24(8-9-25(15)23-17)19(27)22-14-6-1-2-7-14/h3-5,10,14H,1-2,6-9,11H2,(H2,21,26)(H,22,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair