null

SMILES: Cc1nc(cs1)-c1ccc(NC(=O)N2CCn3nc(c(C(N)=O)c3C2)-c2cccc(Cl)c2)cc1

InChI Key: InChIKey=CXFBJOVPDWYDAA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302816 (2-(3-Chlorophenyl)-N5- (4-(2-methylthiazol-4- yl)p...) Show SMILES Cc1nc(cs1)-c1ccc(NC(=O)N2CCn3nc(c(C(N)=O)c3C2)-c2cccc(Cl)c2)cc1 |$;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C24H21ClN6O2S/c1-14-27-19(13-34-14)15-5-7-18(8-6-15)28-24(33)30-9-10-31-20(12-30)21(23(26)32)22(29-31)16-3-2-4-17(25)11-16/h2-8,11,13H,9-10,12H2,1H3,(H2,26,32)(H,28,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM302816 (2-(3-Chlorophenyl)-N5- (4-(2-methylthiazol-4- yl)p...) Show SMILES Cc1nc(cs1)-c1ccc(NC(=O)N2CCn3nc(c(C(N)=O)c3C2)-c2cccc(Cl)c2)cc1 |$;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C24H21ClN6O2S/c1-14-27-19(13-34-14)15-5-7-18(8-6-15)28-24(33)30-9-10-31-20(12-30)21(23(26)32)22(29-31)16-3-2-4-17(25)11-16/h2-8,11,13H,9-10,12H2,1H3,(H2,26,32)(H,28,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair