null

SMILES: CC(C)(O)[C@H]1C[C@@H](Nc2[nH+]c(Nc3ccnc(c3)C#N)ncc2-c2nc3ccccc3s2)[C@H](O)[C@@H]1O

InChI Key: InChIKey=CUHUFYNRHAILNQ-QAKNJHSXSA-O

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM302973 (US9598440, 114) Show SMILES CC(C)(O)[C@H]1C[C@@H](Nc2[nH+]c(Nc3ccnc(c3)C#N)ncc2-c2nc3ccccc3s2)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C25H25N7O3S/c1-25(2,35)16-10-18(21(34)20(16)33)30-22-15(23-31-17-5-3-4-6-19(17)36-23)12-28-24(32-22)29-13-7-8-27-14(9-13)11-26/h3-9,12,16,18,20-21,33-35H,10H2,1-2H3,(H2,27,28,29,30,32)/p+1/t16-,18+,20+,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP. US Patent					Assay Description Procedure: A 20 μl reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (R...				US Patent US9598440 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T6V
					More data for this Ligand-Target Pair