BDBM303677 N-[5-(2- cyclopentylethyl)-1,3,4- thiadiazol-2-yl]-1-[4- (morpholinomethyl) phenyl]-5-oxo- pyrrolidine-3- carboxamide::US10138230, Example F107

SMILES: O=C(Nc1nnc(CCC2CCCC2)s1)C1CN(C(=O)C1)c1ccc(CN2CCOCC2)cc1

InChI Key: InChIKey=OPSQOIQCAZWWHM-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM303677 (N-[5-(2- cyclopentylethyl)-1,3,4- thiadiazol-2-yl]...) Show SMILES O=C(Nc1nnc(CCC2CCCC2)s1)C1CN(C(=O)C1)c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C25H33N5O3S/c31-23-15-20(24(32)26-25-28-27-22(34-25)10-7-18-3-1-2-4-18)17-30(23)21-8-5-19(6-9-21)16-29-11-13-33-14-12-29/h5-6,8-9,18,20H,1-4,7,10-17H2,(H,26,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...				US Patent US10138230 (2018) BindingDB Entry DOI: 10.7270/Q27S7QV8
					More data for this Ligand-Target Pair