BDBM304036 2-[2-(4-FLuorophenyl)-1H-benzimidazol-5-yl]-5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazine::US10138245, Example 7

SMILES: Cc1cnc(C)c2nc(nn12)-c1ccc2[nH]c(nc2c1)-c1ccc(F)cc1

InChI Key: InChIKey=ACFLSTWPZCAEMB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM304036 (2-[2-(4-FLuorophenyl)-1H-benzimidazol-5-yl]-5,8-di...) Show SMILES Cc1cnc(C)c2nc(nn12)-c1ccc2[nH]c(nc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H15FN6/c1-11-10-22-12(2)20-25-19(26-27(11)20)14-5-8-16-17(9-14)24-18(23-16)13-3-6-15(21)7-4-13/h3-10H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
CELON PHARMA S.A. US Patent					Assay Description Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...				US Patent US10138245 (2018) BindingDB Entry DOI: 10.7270/Q2M32XTX
					More data for this Ligand-Target Pair